The internal or extensive topical use of comfrey cannot be recommended because of numerous reports of liver damage. Public Health Nutr 2000;3:501-8. Comfrey contains chemicals that cause serious liver damage when taken by mouth. 16 Rewards for Life points with this purchase. hollandandbarrett.com is a trading name of Holland & Barrett Retail Limited,. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: Results of a randomized controlled clinical double-blind study. Mazzocchi, A. and Montanaro, F. Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery. Satisfaction. Browse our Sports Hub, Buy 1 get 1 Half Price on Vitamins & Supplements, Buy 1 get 1 Half Price gut health supplements, Contains Comfrey known for its healing properties, Symptomatic treatment of minor sprains and bruises. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. 2021;83:e249209. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. By Megan Nunn, PharmD Smith, D. B., & Jacobson, B. H. (2011). We cover all you need to know in this article. Giannetti, B. M., Staiger, C., Bulitta, M., & Predel, H. G. (2010). We cover all you need to know in this article. Staiger, C. Comfrey root: from tradition to modern clinical trials. However, comfrey can also contain toxic substances called pyrrolizidine alkaloids that cause liver damage, cancer, and death. This is because only a small amount of the pyrrolizidine alkaloids are absorbed through the skin (Jedlinszki et al., 2017). Barna, M., Kucera, A., Hladikova, M., & Kucera, M. (2012). We comply with the HONcode standard for trustworthy health information. Stop using comfrey and call your healthcare provider at once if you have: liver problems-- nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). 1. When considering the use of herbal supplements, seek the advice of your doctor. The recipe makes about 6 small jars. 2004;11(6):470-477. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. In a multicenter, randomized, double-blind, placebo-controlled study with 142 ankle sprain participants, a comfrey root extract applied 4x/day for 8 days improved pain, swelling, and mobility without any adverse reactions (Koll et al., 2004). Frost R, O'meara S, Macpherson H. The external use of comfrey: a practitioner survey. Br J Sports Med. To Use. Please simply create an account before buying/booking any courses. Efficacy of a comfrey root (Symphyti offic. Rad. how to become a school board member in florida ocean deck band schedule View abstract. Medically reviewed by Drugs.com on Feb 8, 2023. Although not examined in clinical trials, comfrey may possess antifungal and anticancer activity. Kuera, M., Barna, M., Horek, O., Kovrikov, J., & Kuera, A. Three clinical studies have provided evidence that ointments containing comfrey root have helped reduce back pain. When buying commercial brands, seek those that have had the pyrrolizidine alkaloids removed, if possible. Rad. Essential oils are a whole new world in themselves & the benefits of using them are widespread. If your healthcare provider recommends it, make sure to use it on intact skin for a small amount of time, and be careful that infants do not ingest it. Efficacy of a comfrey root (Symphyti offic. Efficacy of a comfrey root extract ointment in comparison to a Diclo-fenac gel in the treatment of ankle distortions: Results of an observer-blind, randomized, multicenter study. Select a condition to view a list of vitamins. Other prescription medicines that may harm the liver include: Some supplements may also harm the liver, including: It is essential to carefully read a supplement's ingredient list and nutrition facts panel to know which ingredients and how much of each ingredient is included. Contact your doctor or pharmacist if you have any questions before use. View abstract. Set aside cup for the cream recipe and store the rest in a glass jar. J Chiropr Med. Comfrey is an herb in the Boraginaceae family and has small purple flowers. Natural Standard. Symphytum officinale L, S. asperum Lepechin, S. tuberosum L, Symphytum x uplandicum Nyman. Choose a supplement tested by a trusted third party, such as USP, ConsumerLabs, or NSF when possible. Join rewards for life today and we'll give you 300 points worth 3.00. randomized, placebo-controlled, double-blind, multi-clinical trial. Save the remaining liquid alcohol portion. When buying commercial brands, seek those that have had the pyrrolizidine alkaloids removed, if possible. 2012;20(11):1209-1216. Avoid using comfrey extracts on broken skin or open wounds. Other uses not proven with research have included skin wounds, skin ulcers, cough, sore throat, gum disease, joint pain, diarrhea, and other conditions. 2758955. Comfrey should not be used in place of medication prescribed for you by your doctor. Do not give any herbal/health supplement to a child without medical advice. Adv.Ther 2000;17(4):204-210. doi:10.1002/14651858.CD010538, Smith DB, Jacobson BH. Mosby Elsevier. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. Thank you, {{form.email}}, for signing up. 2020;142:104519. Wien Med Wochenschr. Cochrane Database Syst Rev. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. This perennial can grow up to 4-feet tall. Buy 1 get 1 Half Price on Vitamins & Supplements, Popular Vitamins & Supplements Subscriptions, Buy 1 get 1 Half Price gut health supplements, Guide to sleeping better natural sleeping remedies, Living in the now, gut health & mental wellbeing, The thing that makes you different makes you special, Bhupesh Panchal, Senior Regulatory Affairs Associate, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908267/, http://www.missouribotanicalgarden.org/PlantFinder/PlantFinderDetails.aspx, http://www.sciencedirect.com/science/article/pii/S0965229913001672, http://www.ncbi.nlm.nih.gov/pubmed/22887778, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363250/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631335/, https://pubmed.ncbi.nlm.nih.gov/22887778/, https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-symphytum-officinale-l-radix_en.pdf, http://pennstatehershey.adam.com/content.aspx?productid=107&pid=33&gid=000234. Comfrey oil should be applied topically to parts of the body where you have muscular pain or discomfort. The Herbal Academy makes neither medical claim, nor intends to diagnose or treat medical conditions. Herb & Supplement Guide. Be sure to choose organic carrier oils and essential oils when possible. 2012;(1):41-42. Comfrey oil is a herbal oil that moisturises skin, and that's been used as a healing herb for a long time. Many of those following the folk use of comfrey up to present-day think so. All rights reserved. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. 2007;57(11):712-716. The herbal topical cream was prepared at two different strengths, as an additional measure of efficacy. randomized double-blind study of 278 patients with fresh abrasions, a. topical preparation containing a 10% comfrey leaf extraction applied for 2-3 days reduced wound healing time of adults and children without side effects (Barna et al., 2012). Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin. Osteoarthritis Cartilage. 2758955. Comfrey ( Symphytum officinale) is an attractive ornamental plant used in gardening and medicine. A later study of 133 peoplefound some evidence that a topical combination of comfrey extract and tannic acid led to reduced knee pain. Arzneimittelforschung. 2013;21(6):724-45. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Studies in humans are very limited. Toe was infected and painful. It produces clusters of purple, blue, and white flowers, and it's famous for its long . (2018). Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Please read the Topical Use Safety section of this article (above) before using. Lorem ipsum dolor sit nulla or narjusto laoreet onse ctetur adipisci. Rad. Call your doctor for medical advice about . It can grow up to 5 feet tall. This is done by soaking the root in at least 50% alcohol for a minimum of two weeks. Bhupesh started his career as a Clinical Toxicologist for Public Health England, advising healthcare professionals all around the country on how to manage clinical cases of adverse exposure to supplements, pharmaceuticals, cosmetics, industrial chemicals and agricultural products. As an additional measure of efficacy, groups instructed to use the comfrey preparation for the longest period of time experienced the most improvement. Comfrey may have been applied to the skin in a specific preparation to treat some of these conditions. The review included one study of 220 people with knee osteoarthritis, a degenerative "wear-and-tear" joint condition. Comfrey shouldn't be used in any form during pregnancy or nursing due to the risk of liver damage to infants. Topically applied comfrey oil is associated with a wide range of health benefits and can help with certainissues including: Comfrey oil is good at helping with superficial cuts, scratches, and scrapes. Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. The plant leaves have a lower concentration of PAs than the roots. July 6, 2001. Wien.Med Wochenschr. Potters Herbal Comfrey Oil is a soothing aromatic herbal massage oil. , meaning to grow together. Be sure to choose organic carrier oils and essential oils when possible. Stewart MJ, Steenkamp V. Pyrrolizidine poisoning: a neglected area in human toxicology. Stickel F, Seitz HK. Dietary supplements are not regulated like drugs in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. (2001). June 3, 2022 Posted by: Category: Uncategorized; No Comments . Comfrey (Symphytum officinale) is a plant with yellow or purple flowers found in Europe, Asia, and North America. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This leads to cirrhosis and eventually liver failure. Heat oil in double boiler gently then add beeswax until it melts. Mei N, Guo L, Fu PP, Fuscoe JC, Luan Y, Chen T. Metabolism, genotoxicity, and carcinogenicity of comfrey. Cap, then label the jars with the date made and ingredients. Anotherstudy found that comfrey ointment was superior to placebo in relieving pain and stiffness in osteoarthritis. Registered in England: company no. D'Anchise, R., Bulitta, M., and Giannetti, B. Comfrey extract ointment in comparison to diclofenac gel in the treatment of acute unilateral ankle sprains (distortions). Laslett, L. L., Quinn, S. J., Darian-Smith, E., Kwok, M., Fedorova, T., Korner, H., Steels, E., March, L., and Jones, G. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Therapeutic use of comfrey is limited because of its toxicity. (2001). It also covers side effects, interactions, and what to look for.
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